Bone
mineral density, body mass index and cigarette smoking among Iranian women:
implications for prevention.
BMC Musculoskelet Disord. 2005; 6:34 (ISSN:
1471-2474)
Baheiraei A; Pocock NA; Eisman JA; Nguyen ND;
Nguyen TV
Bone and Mineral Research Program, Garvan
Institute of Medical Research, St Vincent's Hospital, University of New
South Wales, Sydney, Australia.
a.baheiraei@garvan.org.au
BACKGROUND:
While risk factors of osteoporosis in Western populations have been extensively
documented, such a profile has not been well studied in Caucasians of
non-European origin. This study was designed to estimate the modifiable
distribution and determinants of bone mineral density (BMD) among Iranian
women in Australia. METHODS: Ninety women aged 35 years and older completed
a questionnaire on socio-demographic and lifestyle factors. BMD was measured
at the lumbar spine (LS) and femoral neck (FN) using DXA (GE Lunar, WI,
USA), and was expressed in g/cm2 as well as T-score. RESULTS: In multiple
regression analysis, advancing age, lower body mass index (BMI), and smoking
were independently associated with LS and FN BMD, with the 3 factors collectively
accounting for 30% and 38% variance of LS and FN BMD, respectively. LS
and FN BMD in smokers was 8% lower than that in non-smokers. Further analysis
of interaction between BMI and smoking revealed that the effect of smoking
was only observed in the obese group (p = 0.029 for LSBMD and p = 0.007
for FNBMD), but not in the overweight and normal groups. Using T-scores
from two bone sites the prevalence of osteoporosis (T-scores).
Tồn Trữ Tài Liệu Khảo Cứu Y Dược Khoa Của Người
Việt
Bs Nguyễn Ðình Nguyên và Ts Nguyễn Văn Tuấn cùng
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